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The Intervening Effect of Preventive Use of Antibacterials During the Perioperative Period in Neurosurgery

Received: 10 October 2020    Accepted: 22 October 2020    Published: 16 December 2020
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Abstract

Objective: Surgical site infections (SSI) is a serious complication of surgery. Perioperative antibacterial prophylaxis is one of the most effective methods to prevent SSI. The aim of this study was to evaluate the effect of interventions on perioperative antibacterial prophylaxis in neurosurgery. Method: We intervened and assessed the perioperative antibacterial prophylaxis from adult patients with a neurological surgery in the First Affiliated Hospital of Jinan University (Guangzhou, China) between May 2014 and December 2014. A total of 279 neurosurgical cases were chosen among which 145 cases were before intervention and 134 after intervention. This study discussed the indications, selection of varieties, timing of the first dose, and application time of antibacterial drugs before and after intervention. Results: Investigation and analysis were performed in the perioperative antibacterial prophylaxis. Compared with the pre-intervention phase, rationalities of perioperative antibiotics prophylaxis in the post-intervention phase were significantly increased. The rational drug selection and the rational timing of using antibacterial after intervention were significantly increased. In addition, the average duration of antibiotic prophylaxis in the post-intervention phase was significantly shorter than the pre-intervention phase. Conclusion: The intervention of perioperative antibiotics prophylaxis was effective and feasible. It contributed to promoting the rational use of perioperative antibiotics prophylaxis in neurosurgery.

Published in International Journal of Infectious Diseases and Therapy (Volume 5, Issue 4)
DOI 10.11648/j.ijidt.20200504.17
Page(s) 145-148
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Perioperative, Antibiotics Prophylaxis, Surgical Site Infections, Intervention, Neurosurgery

References
[1] Anderson DJ, Kaye KS, Classen D, Arias KM, Podgorny K, Burstin H, Calfee DP, Coffin SE, Dubberke ER, Fraser V, Gerding DN, Griffin FA, Gross P, Klompas M, Lo E, Marschall J, Mermel LA, Nicolle L, Pegues DA, Perl TM, Saint S, Salgado CD, Weinstein RA, Wise R and Yokoe DS. (2008). Strategies to prevent surgical site infections in acute care hospitals. Infect Control Hosp Epidemiol 29 Suppl 1: S51-S61.
[2] Diaz V and Newman J. (2015). Surgical site infection and prevention guidelines: a primer for Certified Registered Nurse Anesthetists. AANA J 83: 63-68.
[3] Ng WK and Awad N. (2015). Performance improvement initiative: prevention of surgical site infection (SSI). BMJ Quality Improvement Reports 4: u203279-u205401.
[4] Orsi GB, Scorzolini L, Franchi C, Mondillo V, Rosa G and Venditti M. (2006). Hospital-acquired infection surveillance in a neurosurgical intensive care unit. Journal of Hospital Infection 64: 23-29.
[5] Bachy M, Bouyer B and Vialle R. (2012). Infections after spinal correction and fusion for spinal deformities in childhood and adolescence. Int Orthop 36: 465-469.
[6] Hogli JU, Garcia BH, Skjold F, Skogen V and Smabrekke L. (2016). An audit and feedback intervention study increased adherence to antibiotic prescribing guidelines at a Norwegian hospital. BMC Infect Dis 16: 96.
[7] Patankar M, Sukumaran S, Chhibba A, Nayak U and Sequeira L. (2012). Comparative in-vitro activity of cefoperazone-tazobactam and cefoperazone-sulbactam combinations against ESBL pathogens in respiratory and urinary infections. J Assoc Physicians India 60: 22-24.
[8] Hagiya H, Tasaka K, Sendo T and Otsuka F. (2015). Clinical ineffectiveness of latamoxef for Stenotrophomonas maltophilia infection. Infect Drug Resist 8: 353-357.
[9] Himebauch AS, Sankar WN, Flynn JM, Sisko MT, Moorthy GS, Gerber JS, Zuppa AF, Fox E, Dormans JP and Kilbaugh TJ. (2016). Skeletal muscle and plasma concentrations of cefazolin during complex paediatric spinal surgery. Br J Anaesth 117: 87-94.
[10] Chen J, Zheng F and Guo R. (2015). Algal Feedback and Removal Efficiency in a Sequencing Batch Reactor Algae Process (SBAR) to Treat the Antibiotic Cefradine. PLoS One 10: e133273.
[11] Feng X, Yun L, Yuan LU, Jian L, Wei-wei Y and Jia Z. (2018). Study on minimum inhibitory concentrations and its influence factors of cefathiamidine. The Chinese Journal of Clinical Pharmacology 34: 25-29.
[12] Van Hise NW, Bryant AM, Hennessey EK, Crannage AJ, Khoury JA and Manian FA. (2016). Efficacy of Oral Vancomycin in Preventing Recurrent Clostridium difficile Infection in Patients Treated with Systemic Antimicrobial Agents. Clin Infect Dis 63: 651-653.
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  • APA Style

    Lianfang Xue, Suishan Qiu, Qinai Zhu, Hui Liu. (2020). The Intervening Effect of Preventive Use of Antibacterials During the Perioperative Period in Neurosurgery. International Journal of Infectious Diseases and Therapy, 5(4), 145-148. https://doi.org/10.11648/j.ijidt.20200504.17

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    ACS Style

    Lianfang Xue; Suishan Qiu; Qinai Zhu; Hui Liu. The Intervening Effect of Preventive Use of Antibacterials During the Perioperative Period in Neurosurgery. Int. J. Infect. Dis. Ther. 2020, 5(4), 145-148. doi: 10.11648/j.ijidt.20200504.17

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    AMA Style

    Lianfang Xue, Suishan Qiu, Qinai Zhu, Hui Liu. The Intervening Effect of Preventive Use of Antibacterials During the Perioperative Period in Neurosurgery. Int J Infect Dis Ther. 2020;5(4):145-148. doi: 10.11648/j.ijidt.20200504.17

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  • @article{10.11648/j.ijidt.20200504.17,
      author = {Lianfang Xue and Suishan Qiu and Qinai Zhu and Hui Liu},
      title = {The Intervening Effect of Preventive Use of Antibacterials During the Perioperative Period in Neurosurgery},
      journal = {International Journal of Infectious Diseases and Therapy},
      volume = {5},
      number = {4},
      pages = {145-148},
      doi = {10.11648/j.ijidt.20200504.17},
      url = {https://doi.org/10.11648/j.ijidt.20200504.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20200504.17},
      abstract = {Objective: Surgical site infections (SSI) is a serious complication of surgery. Perioperative antibacterial prophylaxis is one of the most effective methods to prevent SSI. The aim of this study was to evaluate the effect of interventions on perioperative antibacterial prophylaxis in neurosurgery. Method: We intervened and assessed the perioperative antibacterial prophylaxis from adult patients with a neurological surgery in the First Affiliated Hospital of Jinan University (Guangzhou, China) between May 2014 and December 2014. A total of 279 neurosurgical cases were chosen among which 145 cases were before intervention and 134 after intervention. This study discussed the indications, selection of varieties, timing of the first dose, and application time of antibacterial drugs before and after intervention. Results: Investigation and analysis were performed in the perioperative antibacterial prophylaxis. Compared with the pre-intervention phase, rationalities of perioperative antibiotics prophylaxis in the post-intervention phase were significantly increased. The rational drug selection and the rational timing of using antibacterial after intervention were significantly increased. In addition, the average duration of antibiotic prophylaxis in the post-intervention phase was significantly shorter than the pre-intervention phase. Conclusion: The intervention of perioperative antibiotics prophylaxis was effective and feasible. It contributed to promoting the rational use of perioperative antibiotics prophylaxis in neurosurgery.},
     year = {2020}
    }
    

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    T1  - The Intervening Effect of Preventive Use of Antibacterials During the Perioperative Period in Neurosurgery
    AU  - Lianfang Xue
    AU  - Suishan Qiu
    AU  - Qinai Zhu
    AU  - Hui Liu
    Y1  - 2020/12/16
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    DO  - 10.11648/j.ijidt.20200504.17
    T2  - International Journal of Infectious Diseases and Therapy
    JF  - International Journal of Infectious Diseases and Therapy
    JO  - International Journal of Infectious Diseases and Therapy
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    EP  - 148
    PB  - Science Publishing Group
    SN  - 2578-966X
    UR  - https://doi.org/10.11648/j.ijidt.20200504.17
    AB  - Objective: Surgical site infections (SSI) is a serious complication of surgery. Perioperative antibacterial prophylaxis is one of the most effective methods to prevent SSI. The aim of this study was to evaluate the effect of interventions on perioperative antibacterial prophylaxis in neurosurgery. Method: We intervened and assessed the perioperative antibacterial prophylaxis from adult patients with a neurological surgery in the First Affiliated Hospital of Jinan University (Guangzhou, China) between May 2014 and December 2014. A total of 279 neurosurgical cases were chosen among which 145 cases were before intervention and 134 after intervention. This study discussed the indications, selection of varieties, timing of the first dose, and application time of antibacterial drugs before and after intervention. Results: Investigation and analysis were performed in the perioperative antibacterial prophylaxis. Compared with the pre-intervention phase, rationalities of perioperative antibiotics prophylaxis in the post-intervention phase were significantly increased. The rational drug selection and the rational timing of using antibacterial after intervention were significantly increased. In addition, the average duration of antibiotic prophylaxis in the post-intervention phase was significantly shorter than the pre-intervention phase. Conclusion: The intervention of perioperative antibiotics prophylaxis was effective and feasible. It contributed to promoting the rational use of perioperative antibiotics prophylaxis in neurosurgery.
    VL  - 5
    IS  - 4
    ER  - 

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Author Information
  • Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Laboratory Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China

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