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Types of Tuberculosis and Factors Associated with Treatment Outcome and Mortality in the Obuasi Municipality of Ashanti Region, Ghana

Introduction: Tuberculosis (TB) affects all persons in all countries of the world. Treatment outcomes remain a global indicator for measuring a country’s progress towards elimination of tuberculosis. Objective: The study was conducted to determine the distribution of TB by type and factors associated with treatment outcomes and mortality among a cohort of patients who received treatment for this disease between January 2015-December 2017 in the Obuasi municipality of Ghana. Results: The distribution of TB type were as follows: smear positive pulmonary TB (SPPTB), 50.0%, clinically diagnosed (smear negative) pulmonary TB 46.2%, extra-pulmonary TB 3.8% and 114 (19.83%) TB+HIV comorbidity. About 157 (27.30%) of TB patients were not screened for HIV. Successful treatment outcome rate was 77.20%. Unsuccessful treatment outcome rate was 22.80%; 7.90% defaulted, whereas 13.77% died, 0.90% treatment failure and 0.23% transferred out. In multivariable analysis, TB-HIV co-morbidity (aOR=3.37, 95% CI=1.50-7.57, p=0.003) was associated with unsuccessful treatment outcome and mortality (aOR=3.38, 95% CI=1.60-7.12, p=0.001). HIV infection reduced the likelihood of patient having successful treatment outcome whilst increasing the risk of mortality. Noncompliance with enhanced surveillance of screening all TB patients for HIV was common.

Factors, Tuberculosis, Types, TB-HIV Co-morbidity, Treatment Outcomes, Mortality, Ghana

Daniel Yeboah Asiamah, Georgina Frimpong Siraa, Obed Kumi, Williams Domechele, Philip Teg-Nefaah Tabong. (2023). Types of Tuberculosis and Factors Associated with Treatment Outcome and Mortality in the Obuasi Municipality of Ashanti Region, Ghana. International Journal of Infectious Diseases and Therapy, 8(4), 127-131.

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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