Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia

Rediet Ajebu Nurfeta; Tsion Habtamu Ababiya; Nebiyou Yemanebrhane Woldeamanuele; Robel Habtamu Ababiya; Bezaye Lemma Deregasso; Lijalem Abera Tema; Selamawit Seifu Hailu; Dereje Kebede Shane; Bemnet Gossaye Teka; Tsion Andrias Lechebo; Saron Negasi Gidey; Eleni Asfaw Kebede

doi:doi:10.11648/j.ijidt.20240904.11

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| Peer-Reviewed

Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia

Rediet Ajebu Nurfeta

, Tsion Habtamu Ababiya

, Nebiyou Yemanebrhane Woldeamanuele, Robel Habtamu Ababiya

, Bezaye Lemma Deregasso, Lijalem Abera Tema

, Selamawit Seifu Hailu, Dereje Kebede Shane, Bemnet Gossaye Teka, Tsion Andrias Lechebo, Saron Negasi Gidey

, Eleni Asfaw Kebede^*

Published in International Journal of Infectious Diseases and Therapy (Volume 9, Issue 4)

Received: 1 September 2024 Accepted: 18 September 2024 Published: 10 October 2024

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Abstract

Background: Tuberculosis (TB) remains a leading cause of morbidity and mortality in Ethiopia, with treatment success rates consistently below the WHO target. Various factors contribute to poor treatment outcomes. Objective: To assess treatment outcomes for TB and associated factors at Zewditu Memorial Hospital (ZMH) from 2017 to 2021. Methods: An institutional-based analytical cross-sectional study was conducted using TB logbook data. After bivariable analysis, clinically relevant variables and variables with a p-value < 0.2 were included in multivariable logistic regression analysis. Statistical significance was set at p-value < 0.05. Results: The overall successful treatment outcome (cured or completed) was 197 (83.1%). Factors significantly associated with poor treatment outcomes included age group 35 to 44 years (AOR=4.663; 95% CI: 1.215-17.901), extrapulmonary TB (AOR=3.451; 95% CI: 1.172-10.16), and registration in 2019 (AOR=4.367; 95% CI: 1.2-15.87). Conclusion: The treatment success rate falls short of the national target of 85%, highlighting the need for targeted improvements in TB management. The associations with age and extrapulmonary TB emphasize the necessity for focused control measures. Strengthening targeted TB programs at ZMH is recommended.

Published in	International Journal of Infectious Diseases and Therapy (Volume 9, Issue 4)
DOI	10.11648/j.ijidt.20240904.11
Page(s)	55-62
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

TB Treatment, Treatment Outcomes, Zewditu Memorial Hospital, Extrapulmonary TB

References

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Cite This Article

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APA Style

Nurfeta, R. A., Ababiya, T. H., Woldeamanuele, N. Y., Ababiya, R. H., Deregasso, B. L., et al. (2024). Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia. International Journal of Infectious Diseases and Therapy, 9(4), 55-62. https://doi.org/10.11648/j.ijidt.20240904.11

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ACS Style

Nurfeta, R. A.; Ababiya, T. H.; Woldeamanuele, N. Y.; Ababiya, R. H.; Deregasso, B. L., et al. Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia. Int. J. Infect. Dis. Ther. 2024, 9(4), 55-62. doi: 10.11648/j.ijidt.20240904.11

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AMA Style

Nurfeta RA, Ababiya TH, Woldeamanuele NY, Ababiya RH, Deregasso BL, et al. Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia. Int J Infect Dis Ther. 2024;9(4):55-62. doi: 10.11648/j.ijidt.20240904.11

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@article{10.11648/j.ijidt.20240904.11,
  author = {Rediet Ajebu Nurfeta and Tsion Habtamu Ababiya and Nebiyou Yemanebrhane Woldeamanuele and Robel Habtamu Ababiya and Bezaye Lemma Deregasso and Lijalem Abera Tema and Selamawit Seifu Hailu and Dereje Kebede Shane and Bemnet Gossaye Teka and Tsion Andrias Lechebo and Saron Negasi Gidey and Eleni Asfaw Kebede},
  title = {Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia
},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {9},
  number = {4},
  pages = {55-62},
  doi = {10.11648/j.ijidt.20240904.11},
  url = {https://doi.org/10.11648/j.ijidt.20240904.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20240904.11},
  abstract = {Background: Tuberculosis (TB) remains a leading cause of morbidity and mortality in Ethiopia, with treatment success rates consistently below the WHO target. Various factors contribute to poor treatment outcomes. Objective: To assess treatment outcomes for TB and associated factors at Zewditu Memorial Hospital (ZMH) from 2017 to 2021. Methods: An institutional-based analytical cross-sectional study was conducted using TB logbook data. After bivariable analysis, clinically relevant variables and variables with a p-value Results: The overall successful treatment outcome (cured or completed) was 197 (83.1%). Factors significantly associated with poor treatment outcomes included age group 35 to 44 years (AOR=4.663; 95% CI: 1.215-17.901), extrapulmonary TB (AOR=3.451; 95% CI: 1.172-10.16), and registration in 2019 (AOR=4.367; 95% CI: 1.2-15.87). Conclusion: The treatment success rate falls short of the national target of 85%, highlighting the need for targeted improvements in TB management. The associations with age and extrapulmonary TB emphasize the necessity for focused control measures. Strengthening targeted TB programs at ZMH is recommended.
},
 year = {2024}
}

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TY  - JOUR
T1  - Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia

AU  - Rediet Ajebu Nurfeta
AU  - Tsion Habtamu Ababiya
AU  - Nebiyou Yemanebrhane Woldeamanuele
AU  - Robel Habtamu Ababiya
AU  - Bezaye Lemma Deregasso
AU  - Lijalem Abera Tema
AU  - Selamawit Seifu Hailu
AU  - Dereje Kebede Shane
AU  - Bemnet Gossaye Teka
AU  - Tsion Andrias Lechebo
AU  - Saron Negasi Gidey
AU  - Eleni Asfaw Kebede
Y1  - 2024/10/10
PY  - 2024
N1  - https://doi.org/10.11648/j.ijidt.20240904.11
DO  - 10.11648/j.ijidt.20240904.11
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 55
EP  - 62
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20240904.11
AB  - Background: Tuberculosis (TB) remains a leading cause of morbidity and mortality in Ethiopia, with treatment success rates consistently below the WHO target. Various factors contribute to poor treatment outcomes. Objective: To assess treatment outcomes for TB and associated factors at Zewditu Memorial Hospital (ZMH) from 2017 to 2021. Methods: An institutional-based analytical cross-sectional study was conducted using TB logbook data. After bivariable analysis, clinically relevant variables and variables with a p-value Results: The overall successful treatment outcome (cured or completed) was 197 (83.1%). Factors significantly associated with poor treatment outcomes included age group 35 to 44 years (AOR=4.663; 95% CI: 1.215-17.901), extrapulmonary TB (AOR=3.451; 95% CI: 1.172-10.16), and registration in 2019 (AOR=4.367; 95% CI: 1.2-15.87). Conclusion: The treatment success rate falls short of the national target of 85%, highlighting the need for targeted improvements in TB management. The associations with age and extrapulmonary TB emphasize the necessity for focused control measures. Strengthening targeted TB programs at ZMH is recommended.

VL  - 9
IS  - 4
ER  -

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Author Information

Rediet Ajebu Nurfeta

Department of Internal Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

Contact Email

http://orcid.org/0009-0003-5672-7989
Tsion Habtamu Ababiya

Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

Contact Email

http://orcid.org/0009-0003-9698-674X
Nebiyou Yemanebrhane Woldeamanuele

Ethiopian Public Health Institute, Addis Ababa, Ethiopia

Contact Email
Robel Habtamu Ababiya

Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

Contact Email

http://orcid.org/0009-0005-9864-5783
Bezaye Lemma Deregasso

Department of Internal Medicine, Hawassa University Referral Hospital, Hawassa, Ethiopia

Contact Email
Lijalem Abera Tema

Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

Contact Email

http://orcid.org/0009-0000-5442-1386
Selamawit Seifu Hailu

Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

Contact Email
Dereje Kebede Shane

Department of Internal Medicine, Wachemo University, Hossana, Ethiopia

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Bemnet Gossaye Teka

School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia

Contact Email
Tsion Andrias Lechebo

School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia

Contact Email
Saron Negasi Gidey

School of Medicine, Mekelle University, Mekelle, Ethiopia

Contact Email

http://orcid.org/0009-0009-7489-4549
Eleni Asfaw Kebede

School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia

Contact Email

http://orcid.org/0009-0004-2503-1070

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Plain Text BibTeX RIS

APA Style

Nurfeta, R. A., Ababiya, T. H., Woldeamanuele, N. Y., Ababiya, R. H., Deregasso, B. L., et al. (2024). Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia. International Journal of Infectious Diseases and Therapy, 9(4), 55-62. https://doi.org/10.11648/j.ijidt.20240904.11

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ACS Style

Nurfeta, R. A.; Ababiya, T. H.; Woldeamanuele, N. Y.; Ababiya, R. H.; Deregasso, B. L., et al. Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia. Int. J. Infect. Dis. Ther. 2024, 9(4), 55-62. doi: 10.11648/j.ijidt.20240904.11

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AMA Style

Nurfeta RA, Ababiya TH, Woldeamanuele NY, Ababiya RH, Deregasso BL, et al. Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia. Int J Infect Dis Ther. 2024;9(4):55-62. doi: 10.11648/j.ijidt.20240904.11

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@article{10.11648/j.ijidt.20240904.11,
  author = {Rediet Ajebu Nurfeta and Tsion Habtamu Ababiya and Nebiyou Yemanebrhane Woldeamanuele and Robel Habtamu Ababiya and Bezaye Lemma Deregasso and Lijalem Abera Tema and Selamawit Seifu Hailu and Dereje Kebede Shane and Bemnet Gossaye Teka and Tsion Andrias Lechebo and Saron Negasi Gidey and Eleni Asfaw Kebede},
  title = {Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia
},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {9},
  number = {4},
  pages = {55-62},
  doi = {10.11648/j.ijidt.20240904.11},
  url = {https://doi.org/10.11648/j.ijidt.20240904.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20240904.11},
  abstract = {Background: Tuberculosis (TB) remains a leading cause of morbidity and mortality in Ethiopia, with treatment success rates consistently below the WHO target. Various factors contribute to poor treatment outcomes. Objective: To assess treatment outcomes for TB and associated factors at Zewditu Memorial Hospital (ZMH) from 2017 to 2021. Methods: An institutional-based analytical cross-sectional study was conducted using TB logbook data. After bivariable analysis, clinically relevant variables and variables with a p-value Results: The overall successful treatment outcome (cured or completed) was 197 (83.1%). Factors significantly associated with poor treatment outcomes included age group 35 to 44 years (AOR=4.663; 95% CI: 1.215-17.901), extrapulmonary TB (AOR=3.451; 95% CI: 1.172-10.16), and registration in 2019 (AOR=4.367; 95% CI: 1.2-15.87). Conclusion: The treatment success rate falls short of the national target of 85%, highlighting the need for targeted improvements in TB management. The associations with age and extrapulmonary TB emphasize the necessity for focused control measures. Strengthening targeted TB programs at ZMH is recommended.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Tuberculosis Treatment Outcomes and Associated Factors at Zewditu Memorial Hospital, Ethiopia

AU  - Rediet Ajebu Nurfeta
AU  - Tsion Habtamu Ababiya
AU  - Nebiyou Yemanebrhane Woldeamanuele
AU  - Robel Habtamu Ababiya
AU  - Bezaye Lemma Deregasso
AU  - Lijalem Abera Tema
AU  - Selamawit Seifu Hailu
AU  - Dereje Kebede Shane
AU  - Bemnet Gossaye Teka
AU  - Tsion Andrias Lechebo
AU  - Saron Negasi Gidey
AU  - Eleni Asfaw Kebede
Y1  - 2024/10/10
PY  - 2024
N1  - https://doi.org/10.11648/j.ijidt.20240904.11
DO  - 10.11648/j.ijidt.20240904.11
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 55
EP  - 62
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20240904.11
AB  - Background: Tuberculosis (TB) remains a leading cause of morbidity and mortality in Ethiopia, with treatment success rates consistently below the WHO target. Various factors contribute to poor treatment outcomes. Objective: To assess treatment outcomes for TB and associated factors at Zewditu Memorial Hospital (ZMH) from 2017 to 2021. Methods: An institutional-based analytical cross-sectional study was conducted using TB logbook data. After bivariable analysis, clinically relevant variables and variables with a p-value Results: The overall successful treatment outcome (cured or completed) was 197 (83.1%). Factors significantly associated with poor treatment outcomes included age group 35 to 44 years (AOR=4.663; 95% CI: 1.215-17.901), extrapulmonary TB (AOR=3.451; 95% CI: 1.172-10.16), and registration in 2019 (AOR=4.367; 95% CI: 1.2-15.87). Conclusion: The treatment success rate falls short of the national target of 85%, highlighting the need for targeted improvements in TB management. The associations with age and extrapulmonary TB emphasize the necessity for focused control measures. Strengthening targeted TB programs at ZMH is recommended.

VL  - 9
IS  - 4
ER  -

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